shift

(redirected from antigenic shift)
Also found in: Dictionary, Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to antigenic shift: Antigenic drift
References in periodicals archive ?
Type A is likely to undergo an antigenic shift if two or more subtypes infect a single host, creating new subtypes based on surface antigens hemagglutinin (H) and neuraminidase (N).
The last epidemic caused by antigenic shift was in 1989/90 and killed 29,000 people in Britain.
To make the person-to-person leap, the virus would need to undergo a molecular "change of clothes," a dramatic process known as an antigenic shift.
The reemergence in 2012 of W135/ST11 strains that had the FetA1-1 marker suggests an antigenic shift that may have involved membrane proteins other than FetA or other surface structures, such as the lipooligosasccharide.
As populations have no immunity to the new subtype, and as no existing vaccines can confer protection, antigenic shift has historically resulted in highly lethal pandemics.
The predominant H3N2 variant has been "uncharacteristically" stable over the last few years and a significant antigenic shift is anticipated, Dr.
The problem is that the predominant H3N2 variant has been "uncharacteristically" stable over the last few years and a significant antigenic shift is anticipated, Dr.
Antigenic shift leads to replacement of circulating strains with new variants that are able to reinfect hosts immune to earlier types; the result is usually a pandemic.