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ISTHMUS. A tongue or strip of land between two seas. Glos. on Law, 37, book 2, tit. 3, of the Dig.

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Computer simulation and validation of the Archimedes Lever hypothesis as a mechanism for aortic isthmus disruption in a case of lateral impact motor vehicle crash: a Crash Injury Research Engineering Network (CIREN) study.
Because of the focal narrowing of the thoracic aorta distal to the left subclavian artery and the pre- and poststenotic dilatation of the aortic knob and aortic isthmus, the left-sided mediastinal border on the posteroanterior chest radiograph can resemble the number 3 to an experienced observer (Figure 1).