The strategy also prevented the reversion of the attenuated
phenotype by mutation or recombination, thus reducing the possibility that the newly created virus strain could evolve back to the pathogenic version.
Removal of the basic cleavage peptide by reverse genetics results in a virus that is attenuated
for embryonated eggs, thus allowing high yields to be attained.
There were increases in LDH, total protein, and EPO levels 2 days after HDM challenge in ad libitum rats compared to levels before antigen challenge (Figure 3); however, such responses were sharply attenuated
in feed-restricted rats.
Because the pattern attenuated
surface vibrations known as Rayleigh waves, the researchers suggest that holes 26 meters across arranged in a pattern over a large area might hinder the much lower-frequency Rayleigh waves caused by earthquakes.
When local audiences go to see King's stable of thoroughbred dancers in his own company, LINES Contemporary Ballet, with their gorgeously attenuated
limbs and hands hanging rapturously from the wrist, they are going as much to gape at the sublime bodies as to meet King's splintered choreography.
Now, Qingke Kong and his colleagues at the Biodesign Institute at Arizona State University have shown how a powerful new class of therapeutics, known as recombinant attenuated
Salmonella vaccines (RASV), can make vaccines safer and more effective.
This effect of diet on tumor growth was significantly attenuated
by metformin, but metformin had no effect on tumor growth of the mice on the control diet.
Production of live attenuated
and inactivated vaccine seed viruses against avian influenza viruses, which have the potential to cause pandemics, and their testing in preclinical studies and clinical trials will establish the principles and ensure manufacturing experience that will be critical in the event of the emergence of such a virus into the human population.
Themes as diverse as kidnapping in Latin America (the title, which translates, roughly, as "catching fish," is taken from the motorway barricades erected by Colombian guerrillas to stop and capture passersby) and the status of the documentary in the age of global information and omnipresent manipulation surface and disappear into the same hazy, attenuated
abstractions from which they emerged.
The virus used must be sufficiently attenuated
, or disabled, so that it doesn't cause disease.
But here, Tina Martin and Eric Midgley's union seemed far too cautious, although her attenuated
phrasing did give way to sparks in her variation, where she let herself be wooed more convincingly by the violin.