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It is anticipated that the perivascular wraps to be developed under the collaboration will also have potential for use with native or autologous grafts as well.
PRF exudates contain good amount of growth factors (transforming growth factor (TGF)-[beta]1, platelet-derived growth factor (PDGF)-[beta], and vascular endothelial growth factor (VEGF)), matrix glycoprotein's (fibronectin and vitronectin), and proteins specialized in increasing cell attachment to biomaterial impregnation, rinsing surgical sites, hydration of graft materials, and for storage of autologous grafts.
For the purposes of this publication, the focus will be on the most common material used: autologous grafts.
Although various types of autologous grafts such as arteries, veins and muscles have been recommended, an ideal conduit has not yet been described.
9) Allografts may be a good alternative to autologous grafts because they eliminate the need for an additional incision, eliminate donor-site morbidity, and decrease operating time.

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