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Related to autonomic symptoms: Autonomic neuropathy
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The observations that triptan therapy is ineffective after allodynia has developed, and triptans are fairly well tolerated in migraineurs with autonomic symptoms; and besides, the higher risk of the development of allodynia and the chronification of migraine in this subgroup are quite remarkable.
Kenny, "The prevalence of autonomic symptoms in dementia and their association with physical activity, activities of daily living and quality of life," Dementia and Geriatric Cognitive Disorders, vol.
Pure small fiber neuropathy (SFN) affects only the small fiber nerves, pure large fiber neuropathy affects only large fiber nerves, and mixed small and large fiber neuropathy affects both types of nerves.[sup][1] Small diameter, thinly myelinated Aa and unmyelinated C fibers are primarily affected by SFN, resulting in sensory and/or autonomic symptoms such as allodynia, hyperalgesia, palpitations, and hyper/hypohidrosis.[sup][1],[2] Traditional nerve conduction studies (NCS) measure the integrity and function of large fibers independent of small fiber function.
All medical records were available, and the neurologists checked for motor disability, such as Parkinsonism (e.g., tremor, rigidity, bradykinesia, and postural instability), cerebellar features (e.g., gait ataxia, limb ataxia, cerebellar dysarthria, and cerebellar oculomotor dysfunction), and autonomic symptoms (e.g., orthostatic hypotension, urinary incontinence, and erectile dysfunction).
All these neurological symptoms and signs were arranged and fitted into 5 diabetic neuropathy stages by the Diabetic Neuropathy Study Group in Japan [38]: (I) no signs and symptoms or one of the following: bilateral foot symptoms, bilateral attenuation of Achilles tendon reflex, and bilateral attenuation of vibration perception; (II) bilateral attenuation of Achilles tendon reflex and bilateral attenuation of vibration perception; (III) II plus bilateral foot symptoms and bilateral attenuation of touch sensation; (IV) III plus autonomic symptoms (orthostatic hypotension, persistent diarrhea, and persistent constipation); and (V) IV plus muscle atrophy or weakness of extensor digitorum brevis (maybe without bilateral foot symptoms).
A recent study has shown that pilomotor nerve fibers display functional impairment in early stages of PD which correlated with severity of autonomic symptoms [21].
One question related to assessment of autonomic symptoms of withdrawal, such as tremors, muscle tone, and startle responses, which was significantly different.
Autonomic symptoms were more marked among women than men.
Balachander and Chandrashekar observed autonomic symptoms in diabetes in order of frequency of postural giddiness(46%) abnormal sweating(38%) nocturnal diarrhea(38%) gastric fullness(20%) and hypoglycaemic unawareness(8%) (11).
A 37-year-old mother of two was referred with a 1-day history of severe ischaemic-type chest pain occurring at rest and associated autonomic symptoms of nausea, vomiting and excessive sweating.
Frequency of HAM-D and HAM-A items in obese patients without a psychiatric diagnosis HAM-D items n (%) Depressed mood HAM-D#1 15 (46.9) Feeling guilt HAM-D#2 15 (46.9) Work and activities HAM-D#7 15 (46.9) fatigue Somatic anxiety HAM-D#11 17 (53.1) General somatic symptoms HAM-D#13 17 (53.1) HAM-A items n (%) Anxious mood HAM-A#1 21 (65.6) Tension HAM-A#2 20 (62.5) insomnia HAM-A#4 15 (46.9) cognitive HAM-A#5 25 (78.1) Depressed mood HAM-A#6 18 (56.2) Somatic anxiety HAM-A#7 20 (62.5) Cardiovascular symptoms HAM-A#8 17 (53.1) Respiratory symptoms HAM-A#9 13 (40.6) Gastrointestinal symptoms HAM-A#10 14 (43.8) Autonomic symptoms HAM-A#12 14 (43.8)