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CONCLUSIONS The isothermal Michael addition polymerizations of N, N'-bismaleimide-4, 4'-diphenylmethane (BMI) and barbituric acid (BTA) with BMI/BTA = 2/1 (mol/mol) in 1-methyl-2-pyrrolidone were investigated independently in this work.
Why was Veronal active, while barbituric acid had no effect?
The apparent concentrations of TNM in the samples were also determined by assaying 200-[micro]L aliquots with barbituric acid as the condensing reagent and quantifying results by comparison with a 56.
These derivatives were synthesized from reaction of 2-pyridine Carbaldehyde with thiobarbituric acid, barbituric acid and dimethyl thiobarbituric acid in the presence of malononitrile (Table 6, rows 4-6) (Fig.
The reagents used in this work include N,N'-bismalei-mide-4,4'-diphenylmethane (BMI, Beil, 95%), N-phenylmaleimide (PMI, Aldrich, 97%), barbituric acid (BTA, Merk, 99%), 2,2'-azobisisobutyronitrile (AIBN, Acros, 98%), N-methyl-2-pyrrolidinone (NMP, Sigma, 99%), N,N-dimethyl formamide (DMF, TEDIA, 99.
Key words: Knoevenagel Adduct, Barbituric acid, Thiobarbituric acid, Urease Inhibition, Antioxidant and Chymotrypsin.
Barbituric acid itself is used as precursor for the syntheses of a wide range of materials such as plastics textiles [11] pigments [12] and vitamin B2 (riboflavin) [13].
Barbituric acid derivatives had been known as potential clinical drugs , nevertheles s , due to the biological importance of barbituric acid and its s tructure variants , medicinal chemis ts throughout the world extens ively work with this molecule to explore potential therapeutic agents .
Keywords: Barbituric acid, antibacterial, chromenopyrimidine diones.