f) Tegument of tail region showed furrows (F), embedding of spines (S) and sloughing (Sl) in which The tegument had been stripped off to expose the basal lamina
It consists of flattened dedifferentiated cells arranged on a well-developed basal lamina
and connected to each other by zonulae adhaerentes.
BioStratum is a world leader in basal lamina
research and is focused on the discovery and development of novel therapeutics for diabetes and cancer.
BioStratum's two lead drug candidates are direct results of basal lamina
research, Pyridorin(TM) for diabetic kidney disease is in Phase II clinical trials, and Angiocol(TM), a novel, proprietary anti- angiogenic targeting cancer is in late stage preclinical development.
It consists of three components: (a) a single layer of squamous epithelial cells, the endothelium; (b) the basal lamina
of the endothelial cells; and (c) the suyenciothclinl layer, consisting of loose connective tissue.
In this period of regeneration, the cells from the basal layer had already initiated the synthesis of the basal lamina
located right beneath the new regenerated epithelium (Figures 2 and 3), which had been lost at the time of the fin amputation.
1,4) The spindle cells demonstrate numerous intermediate filaments, scant cytoplasmic organelles, and lack basal lamina
, dense bodies, fibronexus junctions, and pinocytic vesicles.
The midgut of insects is in general constituted by a single cell layer whose apical portion is usually oriented to the organ lumen and the basal portion is supported by the basal lamina
(Lehane & Billingsley; Sherman, 1998).
A basal lamina
lies between the oocyte base and the hemal sinus.
Research Triangle Park, NC), a worldwide leader in drug development based on basal lamina
research, has signed an agreement granting Genzyme Corporation (Cambridge, MA) an option to obtain a worldwide license under BioStratum's patent rights pertaining to the diagnosis and treatment of Alport syndrome.
The nerve cell components rapidly degenerate, but the supporting cells, called the Schwann cells, divide and remain aligned in columns, which are surrounded by a continuous tube of material called basal lamina
Electron microscopy shows the basaloid component to have desmosomes, rare tonofilaments and loose stellate granules or replicated basal lamina
within the cystic spaces.