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However, the improvement of their benefit-risk ratio represents both a current need and an ongoing challenge.
If the experiments have social value and are scientifically necessary, they will still not be ethical unless the risks are low enough to yield a favorable benefit-risk ratio.
Nor could it assess whether treating cancerfree women offers "a favorable benefit-risk ratio.
Core-sheath nano- and microfibers offer highly tunable, well-controlled release kinetics for therapeutic molecules whose benefit-risk ratio requires local rather than systemic delivery.
EMA's Committee for Medicinal Products for Human Use (CHMP) is reviewing all data linked to the cardiovascular and cutaneous safety concerns, focusing on existing risk-minimisation measures and their effect on the benefit-risk ratio of Protelos and Osseor.