The stem cell-dcrived beta cells
are undergoing trials in animal models, including non-human primates, Melton said.
We were very excited when we found obese animals had three times the amount of SIK2 in their beta cells
, meaning they were working harder to compensate for high blood sugar by turning up SIK2," Dr.
You might expect the effect could be quite dramatic if they had good numbers of beta cells
to begin with.
The present study was designed to observe the role of CCT aqueous seed extract on beta cell
regeneration and intra-islet vasculature in alloxan-induced diabetes, hypothesising that it induced both.
Evidence for proteotoxicity in beta cells
in type 2 diabetes: Toxic islet amyloid oligomers from intracellularly in the secretory pathway.
Insulin resistance was calculated by HOMA-IR and beta cell
function by HOMA-b equation.
In rats, perinatal malnutrition impaired neogenesis and the capacity of beta cell
regeneration but preserved beta cell
proliferation which remained the only choice to increase beta cell
Critical roles for the TSC-mTOR pathway in beta cell
Royal College of Surgeons' Professor Jochen Prehn said: "There is tremendous hope there is capacity to regenerate beta cells
or protect them against immune cell attack.
Tests in mice have shown the mix of three drugs and an antiin-flammatory enzyme renews insulin-producing beta cells
Dr Iain Frame, Diabetes UK's research manager, said: "This research demonstrates that there may have been a substantial improvement in beta cell
GLP-1 stimulates pancreatic beta cells
to increase the secretion of insulin, so GLP-1 has the potential to improve beta cell