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Biochemical markers (Table 1) linked to the ischemic cascade have the potential to predict outcomes before, during, and after stroke.
Background The standard biochemical markers for the diagnosis of acute myocardial infarction (AMI) are elevations in the total creatine kinase (CK) and its MB isoenzyme (CK-MB).
Prospective studies in both younger (early postmenopause) and older populations have demonstrated that increased concentrations of biochemical markers of bone remodeling are related to the short-term rate of bone loss (5 years or less) (4-6).
Biochemical markers can be used to accomplish the same goals that apply to densitometry, he said, with the exception of establishing a diagnosis.
The purpose of the monograph is to give an overview of past, present, and possible future biochemical markers for myocardial injury and to address each marker's analytical, technical, and clinical performance, as well as outcome assessments, including risk stratification.
The use of biochemical markers to diagnose iron-deficient states is problematic in clinical conditions such as the anemia of chronic disease (ACD).
This limitation may be avoided by use of biochemical markers of bone turnover in the serum or urine, which can show the effects of intervention sooner.
Conventional biochemical markers of alcohol abuse (7) determined in this patient were within the reference interval: [gamma]-glutamyltransferase, mean corpuscular volume, aspartate aminotransferase, alanine aminotransferase, and aspartate aminotransferase/alanine aminotransferase ratio.
An important attribute to consider when evaluating the reliability of a biochemical marker for use in long-term patient monitoring is within-subject and assay variability.
Chapters 3 and 4 are a must for every laboratorian who performs biochemical marker testing for MI.

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