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Related to blast cell: Auer rod, band cell, blast cell leukemia
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In addition to rapid reduction of blast cells, morphologic changes including presence of Auer rods in mature cells (Figure 1) and surface marker analysis of peripheral blood and/or bone marrow cells by flow cytometric studies confirmed the evidence of in vivo differentiation of myeloid leukemic cells.
In t(9;11)(p22;q23) or other 11q23 abnormalities 20% or more blast cells should be present to label it as AML.
In our series, retinopathy occurs in 40% when blast cells are less than 20%, while 60% of the patients do not develop retinopathy.
The mean percentage of blast cells in the G2/M phase in the different heparin concentrations at 0, 1, and 2 h are shown in Table 3.
Bone marrow trephine biopsy showed similar features (Figure-1) and 85-90% of blast cells stained positive with Sudan black.
Sections of the bone marrow demonstrated areas of erythroid hyperplasia; however, there was no evidence of malignant lymphoid infiltrates or a significant increase in blast cells.
Bone marrow examination revealed hypercellular marrow and infiltration with blast cells (Figure 1).
Investigation of karyotypic, morphologic and clinical features in patients with acute myeloid leukemia blast cells expressing the neural cell adhesion molecule (CD56).
The marked increase in immature bone marrow precursor B cells, the immature phenotype, and the resemblance of these B cells to blast cells of acute lymphoid leukemia led to molecular determination of the IgH gene status, which did not show a clonal rearrangement, thereby making a neoplastic lymphoproliferative process less likely.