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Related to brain stem reflexes: Oculocephalic reflex
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Brain death can be established only on the basis of two tests that fulfill five legal criteria -- absence of brain activity, state of deep coma, absence of pupil movement, loss of seven brain stem reflexes, and the cessation of natural breathing.
The cardinal features of brain death are apnea, profound coma and unresponsiveness, and absence of brain stem reflexes.
Surgical intervention is contraindicated in patients with an absence of brain stem reflexes, significant vital brain destruction, uncontrolled intracranial pressure, liver failure, and no or poor flow on CT angiography.