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MRI study of posterior fossa structures and brain ventricles in bipolar patients.
According to the classical hypothesis of cerebrospinal fluid (CSF) flow dynamics, CSF is produced within the ventricular system and it circulates toward the subarachnoid space where it is absorbed and a blockage between ventricular and subarachnoid spaces would cause an increase of intraventricular pressure and dilatation of brain ventricles (5).
Laura feared her baby might not survive the birth, or may face major surgery, but as her pregnancy progressed Bella's kidneys developed and went back to the normal range, the hole in her heart was only 1mm so not considered a problem and the brain ventricle stayed only slightly over the cut-off.
In the prenatal period, polyhydramniosis, intrauterine growth retardation, enlarged brain ventricles and brain anomalies are observed.
A novel polymeric nimodipine microparticle, a single dose of EG-1962 is administered directly into the brain ventricles, from where it releases the drug at the site of brain injury over 21-days.