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Paul et al (2012) argue that these tests could be seen as intrusive for healthy breastfed infants who have breast milk jaundice but concede that, at present, there is no other 'validated' way of determining whether there is any underlying pathology behind the prolonged jaundice.
For years physicians have been taught to have the mother discontinue breastfeeding for 48 hours and then re-check the child's jaundice, which should be greatly improved if it is due to breast milk jaundice, and completely unchanged if a more serious disease exists.