Besim Ogretmen's team found that cancer cells
have specific ways to resist dying the way normal cells do.
The technique works by infecting cancer cells
with a genetically modified virus designed to activate a harmless drug, called a pro-drug.
are those in which growth and survival processes are notched up to dangerous, aggressive levels.
When the team blocked the function ofTBK-1 in both the cancerous and healthy cells, cancer cells
died while healthy cells survived.
There exist contradictory data showing both a positive and a negative role of the TRAIL/TRAIL-R system in the regulation of cancer cell
apoptosis, motility, invasiveness, and metastasis.
The cell growth inhibition of these three extracts was examined in human colon cancer, breast cancer, prostate cancer and lung cancer cells
Several protein survival factors were detected within the microenvironment of the ovarian cancer grafts that could prevent autophagy-induced death of ovarian cancer cells
in the laboratory.
In the April 23 British Journal of Cancer, the Pittsburgh team reports similar behavior in prostate cancer cells
following their incubation with liver cells.
Effects of L TX-diol and iso-LTX-diol on MCF-7 breast cancer cell
Extracts from blueberries and blackberries weren't effective against the two cervical cancer cell
lines tested, but they suppressed breast cancer cell
growth--each fruit suppressing a different cell line.
Professor of Oral Pathology Tuula Salo investigates oral cancer and especially the interaction between cancer cells
and their surrounding tissue.
The study explores this communication between precancerous and cancer cells
in the context of an enzyme called PI3K.