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Specifically, 91 of these 129 tumor tissue specimens had CD8 [sup]+ T cells in the cancer nests, with a mean number of 4.
The number of infiltrating CD3 [sup]+ and CD8 [sup]+ T cells in the cancer stroma was clearly higher than that in the cancer nests ( P = 0.
It is common cause that the main trigger for activating dormant breast cancer nests is progestin, so in the premarin-only arm of the WHI, there was 28% lower incidence of invasive BRCA in the women aged 50-69 at start (and 44% less CHD in the women starting under age 60y;) so breast cancer after HRT is very much age dependent.