Also, because his group uses growth factors, fibrinogen, and more
cartilage cells, "I suspect we'll have a better outcome," he asserts.
NeoCart is a cartilage-like, tissue engineered implant created from a patient's own
cartilage cells.
If the work can be replicated in animals and then developed into a clinical therapy, the engineered cells or cartilage grown from stem cells would respond to inflammation by releasing a biologic drug -- the TNF-alpha inhibitor -- that would protect the synthetic
cartilage cells that Guilak's team created and the natural
cartilage cells in specific joints.
The matrix of acetabular cartilage samples demonstrated numerous round hyaline
cartilage cells (nuclei stained blue) in the cartilage lacuna as single cells or isogenous groups [Figure 2]c.
Medics at the University of Basel in Switzerland have successfully transplanted
cartilage cells from the nose to treat patients with severe cartilage damage.
The nonviable cells exhibited degenerative changes in the cartilaginous matrix and empty cartilage lacunae from which the
cartilage cells were lost.
The remarkable thing about stem cells is the fact that when you inject them into a specific area of the body, they know what kinds of cells the body needs -- for example, meniscus cells or
cartilage cells.
The new procedure removes
cartilage cells surgically from the damaged knee and mixes them with specially selected donor stem cells.
The team used a 3D printer to create a titanium mesh scaffold for the ear, which was then seeded with sheep
cartilage cells.
A team of researchers at Kyoto University has succeed in creating cells with the characteristics of
cartilage cells using human skin cells, using a method faster than producing them from stem cells, according to a study published Thursday in the U.
Ian Clark, professor of musculoskeletal biology at the Norwich university, said: "We have shown that this works in the three laboratory models we have tried, in
cartilage cells, tissue and mice.
But after having
cartilage cells applied to the damaged area during surgery, he was chosen to play for Hungary in a 15-16 defeat to Cyprus in the European Nations Cup.
