For the estimation of case fatality rates, we used the total number of deaths from MD as numerator and the total number of confirmed cases of MD as denominator.
However, incidence and case fatality rates of MD remain high with a wide gap in the risk of disease between poor and affluent areas pointing to the need for periodic adjustments and revaluations of the current strategy.
Case fatality rates for the three conditions are automatically calculated for each level of the health system (facility, district, provincial and national).
For this study, data were extracted from the DHIS data files, which are stored in the National Department of Health, focusing on the data related to the three indicators of case fatality rates for diarrhoea, pneumonia and SAM for the financial years 2011/12 to 2016/17.
This study has also found that Glasgow coma scale on admission, infratentorial location of haemorrhage, intraventricular extension of haemorrhage and size of the haematoma were independently associated with high case fatality rate
. In a hospital based study in Argentina,!13) the 30-day mortality was found to be 34.6% while 38.6% had good functional outcome.
Based on available figures, a 20% decrease in the case fatality rate
will be considered proof of clinical efficacy.
Ebola virus and Marburg virus cause serious disease outbreaks with high case fatality rates
. "These findings have already formed the basis of a more potent vaccine, delivered using a harmless chimpanzee cold virus, which is undergoing trials in the USA, UK, Mali, and Uganda in response to the ongoing Ebola virus outbreak," Ledgerwood said.
In addition, case fatality rates
(CFR) are unacceptably high, ranging from 2.3% to 4.7%, reaching much higher levels at district level in many countries (ranging from 1% to 22% in Cameroon, for example).
Both H7N9 and the MERS CoV (coronavirus) have extremely high case fatality rates
difficile infection was not considered a severe disease, and studies performed 15 years ago reported case fatality rates
of 3.0%-3.5% (28,29).
Case fatality rates
were similar in the two groups, at 6% for ceftriaxone and 5% for chloramphenicol, as were clinical failure rates, which were 3% for ceftriaxone and 4% for chloramphenicol (Lancet 2005;366:308-12).
Case fatality rates
dropped during the late 1960s in patients who died within 1 month or 1 year of admission to a hospital but then stopped decreasing thereafter and settled at about 7% and 5%, respectively (BMJ 328:1466-69, 2004).