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In the past three decades, my empirical research has focused on acquiring an understanding of gut microflora ecology, quorum sensing, composition, loops, and processes such as intestinal adherence, colonization, translocation, and cell polarity.
Primary cilia play a central role in cystic disease pathogenesis, and multiple organ involvement is attributed to the primary cilia because they constitute the connection between mechanical sensing and osmotic and visual stimuli, while they manage to control the cell-cycle and epithelial cell polarity via cell signaling processes.
A genetic hierarchy controlling cell polarity, Nat Cell Biol.
Arias, MD, of the Unit of Cell Polarity at Tufts University School of Medicine, stated: "Polarization of hepatocytes critical for hepatocyte production of bile.
31-34) My research clearly shows that nature's plan of commensal microbiotica absolutely cannot tolerate antiquorum tactics that include antimicrobial pharmaceuticals, natural anti-infectives, synthetic vitamins and chemicals, or the indiscriminate use of inorganic minerals that zap cell polarity and jam up the extracellular matrix and lymphatics.
Regulation of Cell Polarity University College London, During Cell Migration MRC Laboratory for Molecular Cell Biology - Julie A.
The cytoskeleton is a diverse, multicomponent framework that plays a fundamental role in many cellular activities including mitosis, cell division, intracellular transport, cell motility, muscle contraction, and the regulation of cell polarity and organization.
The importance of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer.
NEW YORK, July 1, 2015 /PRNewswire/ -- Cell-cell adherens junctions, the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation.
6,13,14) In order to activate deeper capacities for healing via the stem cell niche, we have to focus on cell polarity and its effect on microflora composition, loops, and processes such as intestinal adherence and translocation.
Although almost all cases showed a "pseudoglandular" architecture, mimicking low-grade EMC, close review revealed significantly discordant architecture and cytology characterized by somewhat ragged luminal borders, loss of cell polarity, prominent nucleoli, and nuclear pleomorphism (bizarre enough to prompt a consideration of ESC) (Figure 1, A and B).
Other topics include mechanisms of intracellular scaling, the structural basis of the unfolding protein response, the hormonal modulation of plant immunity, cell polarity as a regulator of cancer cell behavior plasticity, and cardiac regenerative capacity and mechanisms.