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For neutrophils (percentage and MFI) we analyzed only CDllb/CR3, CD14, CD 16, and CD64 [for full definition of cell-surface markers, see Supplemental Material, Table 1 (doi: 10.
To confirm monocyte/macrophage differentiation of the treated cells under the influence of 3-HK and/or the new compound, the expression of cell-surface markers, such as CD11b and CD14, was also studied.
SPECIFID is designed to provide tumor-specific immunotherapy, selectively depleting only malignant B cells by targeting specific cell-surface markers that are present on the tumors of approximately 25 percent of the patients with non- Hodgkin's B-cell lymphoma.