Central necrosis is a reliable radiographic indicator of cervical node metastasis on CT/MRI.
Retiform and stellate purpura with and without
central necrosis is typically seen grossly.
By week 12, 30% of the treated tumors showed small areas of
central necrosis.
More advanced cutaneous lesions feature
central necrosis.
The bulla ruptures and may exude a sort of bloody purulent material, followed by
central necrosis, a dark brown or black eschar, and edema out of proportion to the size of the lesion.
In addition, intravital microscopy using a murine pseudo-orthotopic breast cancer model showed that NPI-2358 induces a rapid decrease in tumor blood flow resulting in tumor vascular collapse and
central necrosis in established tumors.
False negative cases with higher ADC values were encountered in lesions with
central necrosis and haemorrhage in a study conducted by Lalithe Palle and Reddy in 200 patients.
CT scan finding of large cystic lesion may be of variable etiology like brain abscess, hydatid cyst, brain infarction, and tumors with
central necrosis like oligodendrogliomas, tuberculomas, and many more.
Calcification was observed in areas of caseating
central necrosis (Figures 2(a) and 2(b)).
Microscopically, widespread
central necrosis was present (figure 4).
8-cm heterogeneous, multilobulated mass with
central necrosis originating from either the body and tail of the pancreas or the left adrenal gland with compression of adjacent organs (Figure 1).
Focal
central necrosis was seen with few foamy histiocytes especially around the adnexae.