Diameter of
chief cells and oxyphil cells were measured under 100x objective with a horizontal eyepiece micrometre called "graticule." The graticule was calibrated with a stage micrometre.
We detected intracellular localization of this major pathogenicity factor of HP in parietal cells but found no positivity in
chief cells. In addition, we noted obvious VacA/HP positivity in the lumen of gastric glands and the gastric lumen.
The basal layer of the glandular part was predominantly occupied by the
chief cells (CC), intermingling with a few parietal cells (PC).
Fragmentation of gastric mucosa, dissolution of cellular outlines and collapsed
chief cells are few, visible characteristics.
Photomicrograph showing
chief cells with pale eosinophilic cytoplasm and round to oval nuclei surrounded by sustentacular cells (hematoxylin-eosin, original magnification X20).
The
chief cells mainly distributed at the body and the bottom of gland, with low columnar or cubic in shape, which located between the parietal cells.
Oxyphil cells, being less numerous than
chief cells, were distinguished by their dark eosinophilic, granular cytoplasm.
Histologically, there is usually a single mass, which is most often composed of
chief cells that are surrounded by an uninvolved or atrophic rim of parathyroid tissue (figure 1), with or without a separating fibrous connective tissue capsule.
Chief cells normally produce digestive fluids for the stomach.
The other elements of the fundic glands, parietal and
chief cells, were present in variable numbers in the cardia-type mucosa.
Paragangliomas are composed of two cell types:
chief cells and sustentacular cells.
(26,28) These are composed of
chief cells and sustentacular cells in a nesting or zellballen pattern.