chief constituent

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In The Ussr Glass-Ceramics Are Made In This Way, Using Blast-Furnace Slag As The Chief Constituent.
The thematic, tonal, and formal structures of a literary work are a chief constituent of the determinate structure of meaning in that work.
Nevertheless, its chief constituent -- wood -- is still considered to be the best residential building material, according to Trus Joist MacMillan.
AV-1 binds avidly to [eth]-amyloid, the chief constituent of amyloid plaques, which accumulates abnormally in the brains of people with Alzheimer's disease.

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