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Cinnamic acid lowers blood glucose and improves glucose tolerance in non-obese type 2 diabetic rats
For instance geometric isomers of coumaric acid and cinnamic acid inhibit the seed germination of lettuce at each and every concentration.
The antioxidant properties of propolis extracts may be related to their chemical composition, such as the content of flavonoids (including flavones, flavonols, flavanones and dihydroflavonols) and other phenolic compounds (mainly substituted cinnamic acids and their esters) (Moreno et al.
We selected thirteen typical phenolcarboxylic acids (benzoic acid derivatives, cinnamic acid derivatives and their dehydration-condensation products), and found gallic acid, caffeic acid, danshensu, rosmarinic acid and salvianolic acid B showed 50% inhibitory effects on hCOX-2 activity and A549 cells proliferation.
The ortho- and para- phenolic hydroxyl groups in the flavonoids or cinnamic acid derivatives give the compounds more radical scavenging activity [9, 10].
The literature survey revealed that flavone, benzoic acid and cinnamic acid derivatives have previously been reported from this species [7].
In a review of the potential use of allelochemicals as herbicides, Putnam (1988) listed 6 classes of allelochemicals namely alkaloids, benzoxazinones, cinnamic acid derivatives, cyanogenic compounds, ethylene and other seed germination stimulants, and flavonoids which had been isolated from over 30 families of terrestrial and aquatic plants.
A number of natural molecules such as non-polar coumarins (imperatorin and isoimperatorin), myricitrin, gossypin, quercetin, naringin, kaempferol, apigenin, hypericin, cardiospermin, chrysin, cinnamic acid, pcoumaric acid, caffeic acid, ferulic acid, sinapic acid, sanjoinine A, obovatol, magnolol, honokiol and linalool, isolated from plants have shown promising anxiolytic activity (Fernandez et al.
These compounds include hydroxyl cinnamic acid, dihydrocalcones, flavonols, catechins, Oligomericprocianides like triterpenoids and anthocyanins.