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Related to clonal expansion: Clonal selection
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Lignosulfonic acid inhibited mitotic clonal expansion to about 60% of control levels at a concentration of 2.
We used next-generation sequencing to determine the mutation spectra induced by transplacental BaP exposure and to assess clonal expansion in both somatic tissues and sperm.
As described above, clonal expansion in a B or T cell type occurs after it has a productive binding interaction with a non-self ligand.
An inhibitory effect of resveratrol in the mitotic clonal expansion and insulin signaling pathway in the early phase of adipogenesis.
counts in such persons can be on account of reactive or clonal expansion of T-lymphocytes and can confound HIV diagnosis and delay initiation of chemoprophylaxis and HAART.
Clonal expansion of EBV-infected B cells has been found in the thyroid glands of Hashimoto's thyroiditis patients, blood in SLE, cerebrospinal fluid in MS, salivary glands in Sjogren's syndrome, synovium in rheumatoid arthritis, liver in primary biliary cirrhosis and muscle in dermatomyositis and polymyositis.
The C-type thymus or clonal expansion was also detected in atrophic thymuses that were [gamma]-ray induced in [Bcl11b.
Hence, the monotypic nature (with respect to light chain expression) of the HHV8-infected large lymphoid cells does not reflect a clonal expansion or a lymphoma [9,10].
In terms of lung cancer susceptibility, however, our observation that stem cell activation leads to clonal expansion after injury could, in the context of additional mutations, promote the development of cancerous or precancerous lesions from activated stem cells," Giangreco added.
3) B-cell CLL is characterized by clonal expansion of abnormal B lymphocytes.
Some investigators have proposed that idiopathic hypereosinophilia syndrome is a Th2-mediated disease characterized by clonal expansion of a T-cell population able to produce interleukin (IL)-5 and IL-4.
Seborrheic keratosis is considered to represent a clonal expansion, so the lesion qualifies as a neoplasm.