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Related to clot lysis: fibrinolysis, clot retraction, clot retraction test
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Coagulopathic bleeding can be due to the same factors that complicate bleeding in the intraoperative setting, for example, dilution of clotting factors, heparin rebound effect, and pathologic clot lysis.
Effect of recombinant tissue plasminogen activator on clot lysis and ventricular dilation in the treatment of severe intraventricular haemorrhage.
A study of the protection of plasmin from antiplasmin inhibition within an intact fibrin clot during the course of clot lysis.
Direct clot lysis or clot retrieval for rapid recanalization of the affected sinus can now be considered, as a result of recent advancements in interventional neuroradiology (Baker et al.
It also has been associated with more rapid clot lysis than that of urokinase, with no significant difference in hemorrhagic complications (5).
Thiex, senior neurosurgeon in the Department of Neurosurgery at Aachen University Hospital reported on new results on applying PAION's clot busting drug Desmoteplase in a large animal model of haemorrhagic stroke at the 18th International Congress on Fibrinolysis and Proteolysis in San Diego, CA (USA) (Thiex R, Weis J, Schwartz O, Krings T, Rohde V: Minor Edema Formation after DSPA-induced Clot Lysis of Experimental Intracerebral Hemorrhage.
Firms are hoping that results of this trial will clarify the association between rapid clot lysis and the prevention of post-thrombotic syndrome in patients with proximal DVT, as well as demonstrate how PMT may have lower bleeding risks compared with traditional CDT alone," says Darren Navarro, Senior Analyst at MRG.
3% (26/35) of limbs achieved complete clot lysis, and 11.
Recent data indicate that CPU indeed plays an important role in plasminogen activation because it is able to delay tissue plasminogen activator-induced clot lysis in vitro and since inhibition or depletion of CPU enhances the rate of clot lysis (14-16,18,22-24).
Using a sample of whole blood, the benchtop system documents the interaction of platelets with protein coagulation cascade from the time of loading until initial fibrin formation, clot rate strengthening, and fi- brin-platelet binding via GpIIb-IIIa, to eventual clot lysis.
Documented experience with reocclusion following thrombolysis in the AMI population contributed to clinical concerns of reocclusion of the cerebral vessels following clot lysis.