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Table 19: Incidence of EPS Compared to Placebo in the Adjunctive Therapy Bipolar Depression Studies Adverse Event Term Placebo LATUDA 20 to (N=334) 120 mg/day (%) (N=360)(%) All EPS events 13 24 Ail EPS events, 9 14 excluding Akathisia/Restlessness Akathisia 5 11 Dystonia* 1 1 Parkinsonism** 8 13 Restlessness 1 4 Note: Figures rounded to the nearest integer *Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus **Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor
The cogwheel that might take you up dizzying heights to the mountain, might give you a feeling of mild thrill but never is there an element of fear, the funicular that I took to the Gilmer Lake, might have looked like a scary rollercoaster but was really a mild joyride where your heart never missed a beat, the trek that we were warned was 'considerably tough' was pleasant and ironically, it was the simple sounding barefoot blueberry picking trail that left the sole of your feet aching.
However, cogwheel rigidity remained minimally improved and respiration was irregular.
Low-freguency/high-amplitude Tremors are tremors and rapid, rhythmic high-frequency/low-amplitude oscillation tremors Cogwheel movements movements with a segmented quality.
In this context, the frontal harmonic transmission (FHT) (Kaposta, 19848) constitutes an innovative solution that eliminates the two major disadvantages mentioned above, while significantly diminishing the axial gauge as well, given that the flexible cogwheel is shaped as a circular plate with frontal teeth.
Its engineers developed a cogwheel made from two plastics that together achieved optimum friction and wear characteristics.
He told the Committee yesterday of his longstanding problems with alcohol and his subsequent attempts to deal with them, including seeking assistance from his GP, Drinksense and The Cogwheel Trust.
A 78-year-old woman with idiopathic Parkinson disease diagnosed one year before had mild cogwheel rigidity worse on the left side and intermittent pill-rolling tremors mainly in the left hand.
At interview he demonstrated severe bradykinesia, stiffness to the point of suppression of normal lithium tremor, and cogwheel rigidity; oral-buccal dystonia caused speech to be slow and labored.
There will also be the chance to sample the little known wines of Switerland, which are rarely exported, at local vineyards as well as a trip on the cogwheel railway to the highest alpine garden in Europe which boasts more than 1,000 varieties of plants.
The 28-ton HM 25/130 will produce acetal double cogwheel in a four-cavity mold and 8-sec cycle.
A team of engineers at the London Science Museum managed to complete the construction of a cogwheel computer that had been designed, but never built, 170 years earlier by the Victorian scientist and mathematician, Charles Babbage (17911871).