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A 5-year-old's battle with recurring common colds helped scientists identify why some people are more susceptible to the viral infection than others.
Harri HemilEn from the University of Helsinki, Finland, suggests that the optimal formulation of zinc lozenges and the best frequency of their administration should be further investigated, he also instructs common cold patients to test individually whether zinc lozenges are helpful for them: "given the strong evidence of efficacy and the low risk of adverse effects, common cold patients may already be encouraged to try zinc acetate lozenges not exceeding 100 mg of elemental zinc per day for treating their colds.
The ColdSense app, the company points out, is not intended to offer professional medical advice, diagnosis or treatment; it is an engaging and entertaining way to monitor a user's potential risk of exposure to the common cold.
Researchers had available individual patient data for three randomized, placebo-controlled trials in which zinc acetate lozenges were administered to common cold patients.
Both support use of zinc supplementation within 24 hours of onset of the common cold.
Figure 3 shows that the infection rate of common cold in buildings constructed after 1993, in winter, is dependent on the mean ventilation rate.
On average, adults have only a few common cold episodes per year and children have some half a dozen colds per year.
However, the most common causes of the common cold are viruses -- rhinoviruses, corona viruses, and the respiratory syncytial virus (RSV).
Currently available zinc preparations marketed for treatment of the common cold are in lozenge, rather than tablet, form.
Results from two large meta-analyses confirmed that vitamin C supplementation, in doses greater than 200 mg/day, may shorten the duration of common cold symptoms insignificantly by 1 to 4 days.
Patients with stuffed nose and a hacking cough are crowding clinics and doctors are advising people to stay at home as the common cold is very contagious.
The review was restricted to trials examining the therapeutic effect of zinc lozenges on natural common cold infections.