Efron and Robert Tibshirani of the University of Toronto describe the application of the bootstrap procedure and other computationally
intensive techniques to a variety of problems, both old and new, in the July 26 SCIENCE.
In addition, its processors are computationally
equivalent to more standard devices.
The fragments are then assembled computationally
into virtual drug candidates with accurately predicted binding potency and tailored chemical properties.
ASPEED's value proposition is to enable clients with computationally
intensive applications to significantly reduce response times and improve precision.
Hyperscaling technology brings superior scalability and lightening fast run times for computationally
Starting with a protein crystal structure, an in silico collection of 40,000 molecular fragments and one of the world's largest privately-owned Linux-based supercomputer clusters, Locus identifies optimum ligand binding sites on protein targets, computes the binding affinity of molecular fragments to those sites and then links fragments with desirable chemical properties to computationally
assemble virtual drug candidates.
The University of Florida deployed highly dense, thermally efficient rack-mount servers and storage from Rackable Systems in its HPC distributed-memory cluster, as well as at the university's Tier-2 Center, a member of a global grid computing infrastructure that supports the CMS (Compact Muon Solenoid) experiment and other computationally
intensive scientific applications.
Through this integration with Windows Compute Cluster Server 2003, engineers and scientists can now use MathWorks distributed computing tools to prototype, develop and run computationally
and data intensive applications within Microsoft's high-performance, distributed computing environment, bringing the power of supercomputing to the personal and workgroup level.