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Related to conjugate: complex conjugate
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Effectiveness of a 2+1 dose schedule pneumococcal conjugate vaccination programme on invasive pneumococcal disease among children in Norway.
Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis The Lancet 2007; 369: 1179-86.
Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children.
To 45 mL of each released conjugate we added 5 [micro]L of 100 g/L CHAPS in PBS.
Mersana's Fleximer antibody-drug conjugate platform has the potential to lead the emergence of the next generation of antibody-drug conjugates, which address limitations of the prior technologies and offer tremendous benefits to patients.
The most advanced technologies today offer stable linker technology and cytotoxic prodrugs which only become effective once the conjugate has entered the tumor cell by endocytosis and the drug cleared by proteolytic digestion from the conjugate inside the cell.
The conjugate we are developing will hopefully enhance our ability to detect and treat primary cancers sooner, but it may also more accurately identify and inhibit metastatic spread earlier in the course of the disease.
has entered into a collaboration agreement with R&D-Biopharmaceuticals GmbH to develop and commercialize conjugates of the potent anti-cancer compound tubulysin with Insert's proprietary drug delivery system, Cyclosert(TM).
The Company's site specific protein modification platform provides unparalleled control over cargo placement on a protein, cargo orientation and stoichiometry, enabling the creation of conjugate libraries from which homogenous compounds with optimal efficacy, safety, and half-life can be selected.
The company has also developed proprietary antibody-drug conjugate (ADC) technology comprised of highly potent synthetic drugs and stable linkers for attaching the drugs to monoclonal antibodies.
The recent approval of Seattle Genetics' antibody-drug conjugate Adcetris has raised great enthusiasm among stakeholders in this field.