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In this study, a photo-sensitive cubic phase was developed by immobilizing hydrophobically modified poly (vinyl alcohol)-coumarin conjugate in the water channel.
A microplate luminometer (EG&G Berthold Microlumat Plus[TM] Model LB96V) was used to assess the acridinium conjugates.
About one-half to two-thirds of total estrone in the study samples occurred as polar conjugates.
The company has four technologies: engineered mAbs, mAb-drug conjugates, single-chain immunotoxins and antibody-directed enzyme prodrug therapy (ADEPT).
Conjugate vaccines are a major advance in the control of diseases caused by two members of the normal bacterial flora of the human nasopharynx, Streptococcus pneumoniae (pneumococcus) and Haemophilus influenzae type b (Hib).
MVP also announced the publication of an invited scientific report, titled "Next-Generation PEGylation Enables Reduced Immunoreactivity of PEG-Protein Conjugates," inthe June 2012 issue of Drug Development & Delivery.
By providing control over cargo placement, number and orientation as well as good conjugation efficiency, Redwood is able to generate well defined conjugate libraries for identification of superior antibody-drug conjugates and peptide therapeutics.
Nasdaq:SGEN) announced today that it is reporting data on its SGN-70 program and proprietary antibody-drug conjugate (ADC) technology during six poster presentations at the 2006 Annual Meeting of the American Association for Cancer Research (AACR).
The Endocyte-Bristol-Myers Squibb conjugates will be tumor-targeting drugs and are anticipated to spare healthy cells from the toxic effects of chemotherapy.
This funding will be applied to advancing Redwood's site specific protein modification technology for enhancing antibody-drug conjugates and peptide therapeutics.
today announced preclinical efficacy and safety data from multiple programs, including antibodies to novel and potentially important cancer targets (CXCR4, fucosyl-GM1, glypican-3, mesothelin, CD70) and additional research in the area of antibody-drug conjugates.