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Recent studies suggest that acute renal injury as indicated by elevation in serum creatinine level seen after a contrast CT examination may not be due to the contrast material.
Combidex[R], generically known as ferumoxtran-10, is a remarkable contrast material composed of a simple sugar compound, dextran, and an iron component named ultrasmall superparamagnetic iron oxide, abbreviated as USPIO.
With the number of pediatric contrast-enhanced imaging examinations increasing markedly during the past decade in the United States, researchers wanted to determine the safety of the newer nonionic IV contrast materials in children.
Management believes that contraindications to the use of traditional contrast materials should be evaluated more costly.
Furthermore, non-contrast MRA exams help eliminate extravasation, the bursting of a patient's blood vessel causing hazardous contrast materials to be released under the skin and into the body.