deleterious


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deleterious

adj. harmful.

References in periodicals archive ?
depositing or permitting the deposit of a deleterious substance into places that may enter waters frequented by fish (in this case, a storm sewer and a ditch connected to Booming Ground Creek); and
Therefore, it is necessary to understand the perspective of parents and teachers on the presence of deleterious oral habits, thus enabling the conduction of health prevention and promotion actions in the first years of life, both in the family and school environment.
"Hindi naman lahat bakuna 'yung deleterious or dangerous.
Nemo offers population models (island and lattice), traits (neutral markers, deleterious mutations and more), life cycle events (dispersal, mating, aging, selection, etc.) and saving statistics and data as output.
If the SIFT score of each SNP was less than 0.05, the SNP was regarded as being deleterious, which could strongly affect protein function.
Both genome size and the rate of deleterious mutations in functional parts of the genome have previously been determined, and historical data documents human population levels.
Olaparib was tested in a trial of 193 patients who harbored a deleterious or suspected deleterious germline BRCA-associated ovarian cancer who had received prior therapies.
Next, 14 of the 55 missense variants were predicted to be damaging or deleterious by three different software programs (PolyPhen-2, SIFT, and PROVEAN), and 38 of them were predicted to be less stable (l-Mutant 2.0 and MUpro software).
In a letter to then-Prime Minister Tony Blair in February 2005, Charles said the European Union Directive on Herbal Medicinal Products was having a "deleterious effect" on the UK's complementary medicine sector.
The study found that almost 15 percent of triple-negative breast cancer patients had deleterious mutations in predisposition genes.
Geneticists long have bet on the success of sexual reproduction over asexual reproduction based, in a large part, on the process known as Muller's ratchet, the mechanism by which a genome accrues deleterious and irreversible mutations after the host organism has lost its ability to carry out the important gene-shuffling job of recombination.
Therefore, it is crucial to identify deleterious nsSNPs to characterize the genetic basis of diseases, assess individual susceptibility to these diseases, determinate molecular and therapeutic targets, and predict clinical phenotypes.

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