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For ASD, probandwise concordance for monozygotic twins was 77% for 45 male pairs and 50% for 9 female pairs; however, concordance rates for dizygotic twins were 31% for 45 male pairs and 36% for 13 female pairs.
Human longevity is such a phenotype: survival data from monozygotic and dizygotic twins indicate that heritability is about 50 percent for frailty (i.
Two different twin studies have shown higher concordance for IBS in monozygotic than in dizygotic twins.
In the study, researchers tested 74 pairs of monozygotic (MZ, or identical) twins and 35 pairs of dizygotic (DZ, or fraternal) twins to determine the lowest concentration needed for each twin to correctly identify a citric acid solution as sour.
There is a 75% concordance of celiac disease in monozygotic twins, while dizygotic twins are not different from siblings, indicating the strong genetic contribution to disease.
Evidence supporting this hypothesis comes from monozygotic and dizygotic twin studies (Eisenberg et al.
This estimate is based on studies that compared genetically identical, monozygotic twins to nonidentical, dizygotic pairs, for which the concurrence rate can be as low as 2% to 7% (19).
Genetic influence on chronotype was studied utilizing 205 pairs of monozygotic, reared-together twins (aged 41-47 years), 55 pairs of monozygotic twins reared apart (aged 18-68 years), 50 pairs of dizygotic twins reared apart (aged 22- 27 years), and 79 spouses.
Dizygotic concordance rates are much less--about 19% for bipolar disorder and 13% for unipolar depression (Kendler, Pederson, Johnson, Neale, & Maathe, 1993; Schlesser & Altshuler, 1983).
The magnitudes of the genetic and environmental contributions to the variance in a phenotype can be estimated by comparing the concordance rates in monozygotic (MZ) twin pairs and same-sex dizygotic (DZ) twin pairs.
Data were collected from monozygotic and dizygotic twin pair members of the Vietnam Era Twin (VET) Registry who responded to the VA's Survey of Health in 1987.
There are two kinds of twins--monozygotic twins, who are identical, and dizygotic twins, who are nonidentical and are no more alike than brother or sister.