Injury to dorsal root
ganglia alters innervation of spinal cord dorsal horn lamina involved in nociception.
(2011b; 2015; 2016) explored the role of local protein synthesis in regenerating axons, combined acetylcholinesterase and silver method for demonstrating motor endplates, and expression of Akt, MAPK, c-Jun and c-Fos in the dorsal root
ganglia in accelerating motor and sensory functional recovery after crush injury by H.
n5-STZ Diabetic model develops alterations in sciatic nerve and dorsal root
ganglia neurons of Wistar rats.
Abbott's DRG therapy is a form of neurostimulation that specifically targets the dorsal root
ganglion, a structure along the spinal column which is densely populated with nerves that transmit sensory information to the central nervous system.
Cisplatin modulates voltage gated channel currents of dorsal root
ganglion neurons of rats.
In cases where dorsal root
ganglion cells and sensorial fibers extending to the periphery are intact and anatomic-physiologic integrity is protected, normal SNAPs are obtained, whereas in cases where there is damage in proximal axons reaching the spinal cord from dorsal root
ganglion, dermatomal sensory deficit may occur (4).
Kramer, "The dorsal root
ganglion as a therapeutic target for chronic pain," Regional Anesthesia and Pain Medicine, vol.
Several studies specifically targeted ion channels (VGSCs, hyperpolarization-activated cyclic nucleotide-gated channels) in the dorsal root
ganglion that are primarily related to nociception.
The aim of this report is to describe the use of dorsal root
ganglion (DRG) stimulation to treat chronic coccydynia.
Hammond, "Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root
ganglia of the rat," Neuroscience, vol.
Adequate modeling of a pain system in vitro, for example, would require some combination of keratinocytes and nerve endings, cultures of neurons and glial cells in the dorsal root
ganglion (DRG) and the dorsal horn (DH), or other neuronal networks of the brain.
Herpes zoster is caused by reactivation of the varicellazoster virus, which lies within the dorsal root
ganglion of a spinal nerve.