If the injury occurs distal to the dorsal root
ganglion (DRG) (Fig.
11] The prominence of the nucleolus of dorsal root
ganglion cell bodies presumably reflects a high requirement for ribosomal gene transcription, ribosome production, and protein synthesis to maintain their large cell bodies and extensive axonal projections.
Increased NGF has been demonstrated in the bladder, dorsal root
ganglia, and spinal cord following SCI, and administration of exogenous NGF to the bladder or spinal cord can in animals induce detrusor overactivity and increase bladder afferent neuron excitability [4, 13].
The etiology of the trigeminal neuralgia has been the compression of the trigeminal nerve by loop of an artery, a vein or kinking of the nerve by adhesions at the dorsal root
entry zone near it's exit from the pons6-8.
Increased activation of nuclear factor kappa B in rat lumbar dorsal root
ganglion neurons following partial sciatic nerve injuries.
Characteristics of sensory dorsal root
ganglia neurons innervating the lumbar vertebral body in rats.
entry zone lesions for the treatment of post-herpetic neuralgia.
Herpes zoster is a common disease of the dorsal root
ganglia and sensory nerve fibers clinically characterized by unilateral painful vesicular eruption of the skin in a dermatomal distribution.
To investigate the effects of mtDNA depletion in peripheral neuropathy, we have developed a cell model with mtDNA deletion employing dorsal root
ganglion (DRG) neurons, an important neural cell type in the peripheral nervous system.
Chen YW, Tzeng JI, Lin MF3, Hung CH4, Wang JJ5 (2014) Forced treadmill running suppresses postincisional pain and inhibits upregulation of substance P and cytokines in rat dorsal root
They compared the responses to PNS damage and CNS damage in a type of neuron called a dorsal root
ganglion, which connects to both the CNS and the PNS.
10) In chickens, common sites of neurofibromas, neurofibrosarcomas, and neurogenic sarcomas are the skin, dorsal root
ganglia, brachial plexus, brachial nerve, thoracic spinal ganglion, anterior mesenteric and celiac plexus, lumbosacral plexus, radial nerve, kidney, voluntary muscle, spleen, tongue, testis, and adrenal gland.