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This suggests that an effect on autoimmunity might be a sensitive toxic end point (an effect that occurs at doses lower than other adverse effects) for methoxychlor, and therefore of particular interest for risk assessment, o,p'-DDT decreased the time to development of lupus at a dosing rate of 0.
Methadone (Dolophine) can decrease didanosine levels up to 41% (methadone levels remain unchanged): increased dosing of didanosine should be considered.
43] Twenty-five patients were randomized to receive a 500-mg infusion of amifostine 15 minutes prior to chemotherapy dosing.
Succimer dosing commenced within approximately 15 min after administration of the oral [sup.
Dosing continued through pregnancy and the birth and nursing of pups, ending at weaning.