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This suggests that an effect on autoimmunity might be a sensitive toxic end point (an effect that occurs at doses lower than other adverse effects) for methoxychlor, and therefore of particular interest for risk assessment, o,p'-DDT decreased the time to development of lupus at a dosing rate of 0.
Methadone (Dolophine) can decrease didanosine levels up to 41% (methadone levels remain unchanged): increased dosing of didanosine should be considered.
Dosing of the remaining three groups will proceed sequentially, with progressively higher doses to be administered to the next group only if the dosage in the prior lower dose group is determined to be safe and well-tolerated.
Interstudy differences in animal strain, diet, dosing regimens, and even housing conditions were all offered as possible explanations for the discrepancy.
43] Twenty-five patients were randomized to receive a 500-mg infusion of amifostine 15 minutes prior to chemotherapy dosing.
NASDAQ-NMS: AGPH) announced that clinical investigators reported interim results of Phase I safety and dosing studies of its anti-tumor agent AG337 in presentations yesterday at the annual meeting of the American Association for Cancer Research in San Francisco.
After 14 days of dosing with 400 mg of bevirimat tablets administered on top of patients' failing background regimens, an antiviral effect was seen in the bevirimat treatment group.
Succimer dosing commenced within approximately 15 min after administration of the oral [sup.
To date 34 women of the 39 enrolled have completed three months of dosing.