It thus appears that when food continues to arrive following a peck to the DRO discrimination key, durable response
3 percent of patients treated with IMLYGIC achieved a durable response
compared to 2.
95% of patients receiving a durable response
were alive at six months.
Oncolytic virus immunotherapy may become a new approach to melanoma treatment, and the OPTiM study demonstrated durable responses
in talimogene laherparepvec treated patients with metastatic melanoma," said lead investigator Howard L.
Alefacept has the lowest efficacy against psoriasis, but it gives a particularly durable response
in patients who do respond.
Agreement secured on durable response
proportion as primary endpoint
Combinations also need to be shown in preliminary clinical studies to provide greater-than-additive activity or a more durable response
compared to using the agents alone.
The European Marketing Authorization for Evoltra(R) (clofarabine) is for "the treatment of acute lymphoblastic leukemia (ALL) in pediatric patients who have relapsed or are refractory to at least two prior regimens and where there is no other treatment option anticipated to result in a durable response
In terms of drugs in development for advanced melanoma, Medical Oncologists have reported that they have a high level of interest with the combination therapy of Yervoy and Zelboraf, they feel that this therapy could provide a rapid yet durable response
in patients with unresectable (inoperable) or metastatic melanoma.
In two hepatitis B studies, researchers have confirmed that patients treated for one year with PEGASYS(R) (peginterferon alfa-2a (40KD)) have a durable response
that lasts for years after stopping therapy.
Final data on survival and durable response
from AGENDA are expected in the first half of 2011.
Selecta designs tSVP[TM] products to deliver antigen and adjuvant combinations within the same biodegradable nanoparticle, thus ensuring a focused and durable response
while keeping off-target effects at a low level.