In particular, there was greater benefit in patients with ejection fraction below the median of 57%, with a 22% reduction (rate ratio 0.78; 95% CI 0.640.95) and in women, with a 28% reduction (rate ratio 0.73; 95% CI 0.590.90) in the primary endpoint.
Univariate analysis of the comparison revealed that pre-operative ejection fraction (p value 0.010) and cardiogenic shock (p value 0.031) were a significant risk factors for operative mortality.
The echocardiography post-CRT revealed an improved mitral regurgitation and left ventricular function, with an ejection fraction of 34% and no intra or interventricular asynchrony (Figures 5 and 6).
These results have led to a class I, level of evidence A recommendation for exercise training in HF patients regardless of their ejection fraction in recent European Society of Cardiology HF guidelines [2].
The purpose of the study was to compare the QRS score with left ventricular ejection fraction, relate the score to clinical and biochemical estimates of LVEF.
In the publication, the authors noted that, "This degree of improvement is considered atypical for a patient having suffered an ST elevated myocardial infarction (STEMI) with an ejection fraction below 40 percent post reperfusion (stenting)."
Planar radionuclide ventriculography (RVG) also commonly known as multigated acquisition (MUGA) cardiac blood pool scintigraphy has long been a simple and noninvasive method to assess ventricular function and, in particular, left ventricular ejection fraction (LVEF).