They worked together as part of the International League Against Epilepsy (ILAE) Consortium on Complex Epilepsies
. The ILAE Consortium was formed by researchers in 2010, recognizing that the complexity of genetic and environmental factors underlying epilepsy would require research across massive datasets, and therefore unprecedented collaboration on an international scale.
In addition, we were able to pinpoint the 21 most likely epilepsy genes at these loci, with the majority in genetic generalized epilepsies
Notably, people with epilepsy exhibited lower volume in the right thalamus - a region which relays sensory and motor signals, and has previously only been associated with certain epilepsies
- and reduced thickness in the motor cortex, which controls the body's movement.
Mental illness, personality traits and quality of life in epilepsy: Control study of patients with juvenile myoclonic epilepsy and other epilepsies
. Revue Neurologique, 56(12), 608-614.
ILAE classification of the epilepsies
: Position paper of the ILAE Commission for Classification and Terminology.
Moreover, patients with persistent seizures and diagnoses of symptomatic or cryptogenic epilepsies
([section]) have the largest excess mortality (4).
Update on the surgical treatment of the epilepsies
. Neurology 1993;43(8):1612-1617.