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IV infiltration and extravasation fluid leaking into the tissue around an IV site is a key issue as it can result in serious medical complications and even amputation.
Extravasation occurs when an injected medicine escapes from the blood vessels and circulates into surrounding tissues in the body, causing severe damage and serious complications.
Sinan et al, (2005) identified increased contrast extravasations following IV cannulation by non-radiology staff.
Extravasations are leaks of potentially harmful infusates such as chemotherapy medications.
Selection of the main renal artery showed multiple areas of small pseudoaneursym formation and active extravasations with AV fistula formation in the interpolar to upper polar region of the right kidney (Figure 2).
Eight examinations were negative for active extravasation, two of whom showed haemorrhage in second session and were embolized.
Schamberg's purpura may resemble stasis dermatitis, because both processes include inflammation, dilation of capillaries, extravasation of erythrocytes, and hemosiderin deposits.
Schulmeister adds that "infusion pumps should not be used to administer vincristine peripherally as they deliver infusions at higher pressures than gravity infusions and may continue to infuse even though extravasation is occurring.
The patented system prevents moderate to severe contrast extravasations that may seriously injure patients.
Signs of an extravasation are similar to an infiltration and include swelling, discomfort, pain at the site, coolness of skin, and, in addition, blistering (Fieldstein, 1986; MacCara, 1983).
We are extremely pleased to add Savene([R]) to our product portfolio and are confident SpePharm will continue to rapidly grow its sales as we integrate this medically important orphan drug product for the treatment of patients with anthracycline extravasations into our portfolio.
Apricus acquired the rights to Topotarget's Totect, intended for treatment for chemotherapy-induced extravasations, in North and South America, as well as all North and South American assets of Totect.