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Afterwards, rats were anaesthetized by ether inhalation4 and their slow and fast muscles (that is soleus and EDL) were removed intact.
2004) showed that expression of a constitutively active form of NFAT (NFATc1) stimulates expression of the MyHCslow isoforms in regenerating muscles, and inhibits the fast MyHC IIB promoter in fast muscles of the adult.
Similarly, early and regular muscular activity appears to elicit a greater expression of slow MHC in the fast muscles of rodents, but only when the muscle is exposed to damage-regeneration phenomena [50].

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