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Although recent major surgery is considered to be a contraindication for the use of fibrinolytic therapy, several authors have questioned this view for life-threatening patients.
When fibrinolytic therapy is indicated or chosen as the primary reperfusion strategy, it should be administered within 30 minutes of hospital arrival.
Although not statistically significant, survival to hospital discharge was also higher in the fibrinolytic therapy group (19% versus 7%) [33].
Comparison of primary percutaneous coronary intervention and fibrinolytic therapy in ST-segment-elevation myocardial infarction: Bayesian hierarchical meta-analyses of randomized controlled trials and observational studies.
Identification of SVS may help guide therapeutic decisions in terms of indicating whether an occlusive clot is susceptible or resistant to fibrinolytic therapy,[85],[86] as stated, old, platelet-rich and well-organized thrombi formed under flow conditions have been shown to be more resistant to thrombolysis than fresh, fibrin- and red cell-rich clots formed under conditions of stasis,[87] and it is essential to identify the clot composition and time phase; therefore, we can treat different individuals with the most suitable therapy based on clot characteristics.
Collaboratively with Galen Wagner and Rob Christensen, we performed several studies on a small cohort of patients with established MI who received fibrinolytic therapy to establish reperfusion (2).
Francis, "Transport processes in fibrinolysis and fibrinolytic therapy," Thrombosis and Haemostasis, vol.
Both guidelines recommend the use of clopidogrel in patients with STEMI for whom fibrinolytic therapy is planned.
Once a hemorrhagic stroke is ruled out, medical staff must assess the appropriateness of fibrinolytic therapy through the use of a fibrinolytic checklist.
Patients in group 1 were treated with percutaneous coronary intervention, while those in group 2 received fibrinolytic therapy (tPA) according to European Society of Cardiology (ESC) guideline.1
Objective: To confirm that either Fibrinolytic therapy or open decortication which of the two is an effective First line treatment of pleural empyema.
Local fibrinolytic therapy with 10 mg of alteplase (recombinant tissue plasminogen activator-rtPA) was initiated, followed by systemic sodium heparin (250 IU/Kg) to achieve a target activated thromboplastin time between 1.5-fold and 2.0-fold over the normal range.