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Identification of SVS may help guide therapeutic decisions in terms of indicating whether an occlusive clot is susceptible or resistant to fibrinolytic therapy,[85],[86] as stated, old, platelet-rich and well-organized thrombi formed under flow conditions have been shown to be more resistant to thrombolysis than fresh, fibrin- and red cell-rich clots formed under conditions of stasis,[87] and it is essential to identify the clot composition and time phase; therefore, we can treat different individuals with the most suitable therapy based on clot characteristics.
If percutaneous coronary intervention is planned in patients who have been given fibrinolytic therapy previously
Patients who had history of CABG, receiving fibrinolytic therapy, undergoing PCI for non-ST-elevation myocardial infarction (NSTEMI) and those presenting beyond 24 hours following the onset of symptoms were excluded from this analysis.
Fibrinolytic therapy for acute myocardial infarction (AMI) became standard of care fully three decades ago, the best approach being to administer thrombolytic therapy as soon as possible to all patients without contraindications who present within 12 hours of symptom onset and have ST-segment elevation on the ECG or new-onset left bundle-branch block, unless an alternative reperfusion strategy is planned.
Fibrinolytic therapy for mechanical valve thrombosis of aortic prosthesis is a reasonable alternative to surgery in the first trimester of pregnancy.
8226; NQF 0164 CMS60 AMI-7a- Fibrinolytic Therapy Received Within 30 minutes of Hospital Arrival v2
The clinical need is greater in centers without on-site primary PCI, because the implications of false catheterization laboratory activation are not as significant as unnecessary administration of fibrinolytic therapy.
Fibrinolytic Therapy Trialists' (FTT) Collaborative Group (1994) "Indications for Fibrinolytic Therapy in Suspected Acute Myocardial Infarction: Collaborative Overview of Early Mortality and Major Morbidity Results from All Randomized Trials of More than 1,000 Patients.
As with STEMI patients, pre- arrival hospital notification by the transporting EMS unit significantly increase the percentage of patients with acute stroke who receive fibrinolytic therapy.
These include aspirin, P2Y12 platelet inhibitors, other antithrombotic agents, fibrinolytic therapy, and NSAIDs.