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Related to focal disease: focal distance
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The more the number of glomeruli obtained, the easier it becomes to make a diagnosis, and in cases like Focal Segmental Glomerulosclerosis (FSGS), in which diagnosis can be missed if corticomedullary junction is not obtained and other focal diseases, it is imperative that an adequate tissue is obtained.
Histoplasmosis is considered the most common cause of mediastinal fibrosis and almost always produces a focal disease process.
Kabale, Uganda (38), and Nandi, Kenya (39), are reminders that malaria is a focal disease susceptible to many factors that vary by specific location and season.
Atherosclerosis is a focal disease." explains Christopher Zarins.

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