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Anaphylactoid shock due to folinic acid during treatment of metastatic colorectal cancer.
Leucovorin which is folinic acid given with multidose regimen to buffer the side effects of MTX, which can lead to bone marrow depression also.
High-dose methotrexate (HD-MTX) with folinic acid (leucovorin) rescue is an important chemotherapy regimen used commonly for osteosarcoma.
The first experimental group was injected with retinoic acid to induce a defective model, while the second experimental group was concomitantly injected folinic acid to observe its protective effects on retinoic acid-induced defects in the development and hatching process.
However, due to genetic variants in the DHFR enzyme, or variants that can reduce folate, folinic acid and SAMe, BH2 is not converted back into BI-14.
Folinic acid is another natural form of folate useful for certain methylation defects, said Dr.
The chemotherapy regimen of folinic acid, fluorouracil, oxaliplatin (FOLFOX), and cehiximab was initiated.
organophosphates and carbamates), calcium chloride or gluconate (severe hypocalcemia, calcium-channel-blocker overdose, exposure to hydrofluoric acid), glucagon (hypoglycemia), folinic acid (methotrexate overdose), protamine
Seventeen patients were treated with the adjuvant bimonthly regimen of 5FU/LV--high dose Folinic acid (de Gramont Regimen); whereas, six patients were treated with adjuvant monthly regimen of 5FU/LV--low dose Folinic acid(Mayo Clinic Regimen) as follows.
5mg/Tablet Methotrexate Methotrexate Injection 50mg/ Vial (as SodiumSalt) LeucovorinCa Folinic Acid Injection 15mg/2ml in (Calcium Salt) amp.
Methotrexate-induced cytotoxicity and genotoxicity in germ cells of mice: intervention of folic and folinic acid.