are typically considered for poorly soluble APIs, in order to take advantage of lipid solubility, or as line extensions to marketed drugs.
Evolving DDS media from first-generation 2GB products to the 36GB capacity of the new DAT 72 format is the result of consistent improvements in metal particle formulations
, thinner media and improved base films.
Figure 1 shows how much impact an increase in formulation
solids can have on sheet moisture and ultimately line speeds.
VIDEX EC is an enteric coated, once daily formulation
, which, in combination with other antiretroviral agents, is indicated for the treatment of HIV-1 infection in adults whose management requires once-daily administration of didanosine or an alternative didanosine formulation
In a study comparing saquinavir soft-gel/NRTIs versus saquinavir hard-gel/NRTIs, on-treatment analysis showed that at 16 weeks 67% of' patients on the soft-gel formulation
compared to 37% of patients on the hard-gel formulation
had viral loads below 400 copies/mL.
It performs reflectance and transmittance measurements in either a standalone mode using its built-in software, or interfaced to a PC with the company's new WinMatch QC and formulation
software for Windows 95.
In their 16-week, double-blind, placebo-controlled study of 201 men and women with elevated LDL levels, the new formulation
achieved niacin's typical cholesterol reductions -- with almost no ill effects.
EpiTan Limited (ASX: EPT, ADR: EPTNY, XETRA: UR9), Melbourne, Australia has announced that approval has been obtained from the UK's regulatory agency - The Medicines and Healthcare products Regulatory Agency (MHRA) - to begin a human trial for a newly developed topical formulation
for its melanin-inducing drug Melanotan.
There ate many factors that should be taken into consideration when determining what composite mix formulation
should be used:
Overall compounds based on K1446A and reduced oil performed better than the control formulations
Special uv stabilizer formulations
are provided for PE, PP and polybutylene films.