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Abstract presented at this year's ASH meeting reported the initial data from this study demonstrating that administration of Actimab-A (monoclonal antibody HuM195 labeled with actinium 225) in fractionated doses is feasible, safe and has antileukemic activity.
A total of 22 Gy was delivered in fractionated doses to both cerebellopontine angle masses; the dose to the tumor periphery averaged 18 Gy.
Fractionated doses of Gemtuzumab Ozogamicin combined to standard chemotherapy improve event-free and overall survival in newly diagnosed de novo AML patients aged 50-70 years old: A prospective randomized Phase 3 trial from the Acute Leukemia French Association (ALFA) (Sylvie Castaigne, Hypital Andre Mignot; Plenary presentation, Abstract #6, December 11)5