Mutation

(redirected from gene alteration)
Also found in: Dictionary, Thesaurus, Medical, Encyclopedia.

MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

Mentioned in ?

References in periodicals archive ?

Karen had found out about genetic testing to discover whether women - and men - had gene alterations which predisposed them to breast and ovarian cancer, and would enable them to take preventative action, removing their breasts and/or ovaries to remove the risk.

I'm having an op so my kids won't grow up without a mum; KAREN HAS HYSTERECTOMY AND DOUBLE MASTECTOMY TO PREVENT CANCER

7) In this model, leukemia-associated gene alterations were divided into two groups: class I mutations included activating mutations of tyrosine kinase receptors such as FLT3-ITD and oncogenes such as N-Ras as well as inactivation mutations of tumor suppressors including p53, inducing cell proliferation or inhibiting apoptosis.

The molecular basis of myeloid malignancies

The case study and genogram below were collected as part of a qualitative study of BRCA gene alteration carriers of reproductive age as they struggled to integrate genetic testing results and family medical histories with normative life cycle tasks (1) (Werner-Lin, 2007, 2008a).

Family illness narratives of inherited cancer risk: continuity and transformation

Our results would suggest that, similar to direct sequencing, all samples considered to have a gene alteration by microarray analysis should undergo repeat PCR and GeneChip analysis.

Evaluation of oligonucleotide arrays for sequencing of the p53 gene in DNA from formalin-fixed, paraffin-embedded breast cancer specimens

Blood taken from Lesley, in which the gene alteration has been found, will be compared to that of her sisters.

Sisters at the mercy of faulty cancer gene; Two female relatives had already died of the killer disease when Lesley developed ovarian cancer. Now her three sisters wait to see if they, too, are at risk

The World Anti-Doping Agency, which is affiliated with the International Olympic Committee, will discuss gene alteration at a meeting in late September, hoping to nip the issue in the bud and figure out policies.

Rise of the superathlete: altered genes could lead to gigantic football players, towering basketball centers, and huge risks. (sports)

Animal feed and food products in which DNA or protein resulting from gene alteration cannot be detected using existing technologies are exempted from labeling.

Japan Releases New GMO Regulations

Society must also consider the effects of gene alteration on future generations, Walter said.

Genetic breakthrough elicits ethical alarm

However, our preliminary molecular studies now suggest that this gene alteration may in turn influence the activity of several other independent genes required for synthesizing beta-carotene.

High-Beta-Carotene Cauliflower

When we consider the "modern" project of the technological improvement of nature, and the improvement of the functioning of the body (internal nature, so to speak) by gene alteration, we are urged to a serious consideration of the parallels between them.

The Ethics of Human Gene Therapy

We are approaching the time, perhaps ten or twenty years away, when gene alteration will be offered as a service.

Down the animal pharm: splicing away regulations

Its use has been expanded to treat patients with advanced, or metastatic, non-small-cell lung cancer whose tumours have an ROS-1 gene alteration, which is believed to lead to abnormal cells.