gist


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gist

(Ground for a suit), noun alleged reason, base, basis, basis of argument, basis of litigation, cardinal point, cause, cause of action, essential ground, essential matter, essential part, focal point of the complaint, foundation of a suit, gravamen, gravamen of a charge, gravamen of the complaint, great point, ground, important point, keystone, main charge, main point, object of the action, pith of a matter, point, principal part, principal point, reason, reason for which suit is commenced, salient point, substance, substantial part of a complaint, sum and substance, ultimate cause
Associated concepts: gist of a cause of action, gist of an offense, gist of the complaint

gist

(Substance), noun backbone, basis, broad meaning, connotation, core, drift, essence, essential meaning, essential part, fundamentals, general meaning, idea conveyed, import, index, intrinsic nature, marrow, matter, pith, primary meaning, purport, quiddity, quintessence, real content, reality, root, sense, spirit, substantial meaning, sum and substance, tenor, true meaning, vital principle
See also: center, connotation, content, contents, context, essence, gravamen, import, main point, meaning, significance, signification, spirit, subject, substance, sum, tenor

gist

the essential point of an action.

GIST, pleading. Gist of the action is the essential ground or object of it, in point of law, and without which there is no cause of action. Gould on Pl. c. 4, Sec. 12. But it is observable that the substance or gist of the action is not always the principal cause of the plaintiff Is complaint in point of fact, nor that on which he recovers all or the greatest part of his damages.
     2. It frequently happens that upon that part of his declaration which contains the substance or gist of the, action, he only recovers nominal damages, and he gets his principal satisfaction on account of matter altogether collateral thereto. A familiar instance of this is the case where a father sues the defendant for a trespass for the seduction of his daughter. The gist of the action is the trespass, and the loss of his daughter's services, but the collateral cause is the injury done to his feelings, for which the principal damages are given. In stating the substance or gist of the action, every thing must be averred which is necessary to be proved at the trial. Vide 1 Vin. Ab. 598; 2 Phil. Ev. 1, note. See Bac. Abr. Pleas, B; Doct. P. 85. See Damages, special, in pleading; 1 Vin. At. 598; 2 Phil. Ev. 1, n.

References in periodicals archive ?
Avapritinib has demonstrated broad inhibition of KIT and PDGFRA mutations associated with GIST, including potent activity against activation loop mutations that are associated with resistance to currently approved therapies.
The OES-led Global Innovation through Science and Technology (GIST) initiative catalyzes science, technology, and innovation (STI) activities that support the Administrations economic and national security goals, including by connecting American businesses with premier foreign entrepreneurs in priority emerging markets, helping to build more stable economies, and strengthening American business and investment ties to foreign markets.
In June 2019, the US FDA granted Fast Track Designation to ripretinib for the treatment of patients with advanced GIST who have received prior treatment with imatinib, sunitinib and regorafenib.
- High-impact upcoming events in the GIST space comprise topline Phase III trial results for DCC-2618 and topline Phase I/II trial results for ilixadencel.
Integrated genomic study of quadruple-WT (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).
Treated GIST cells were washed in phosphate-buffered saline (PBS) twice before proteins were extracted and quantified using a BCA kit (Thermo scientific, USA).
Non-epithelial neoplasms of the gastrointestinal tract that do not have the ultrastructural characteristics of smooth muscle cells are known as GISTs. Mazur and Clark in 1983 were the first to describe GISTs.
Objective: To assess the frequency of loss of expression of succinate dehydrogenase-B (SDH-B) in gastrointestinal stromal tumors (GISTS) of our population through immunohistochemistry.
A third prognostic factor in more recent classification systems is considered as the location of GIST.[6],[7] According to the clinical data presented by Wang et al ., the relapse-free survival (RFS) time of small rectal GISTs was significantly different than that in other anatomic sites.
[23] were excluded as they described the CBR without comparison between the different GIST genotypes [22, 23].
In our presented case, this patient had developed a Desmoid tumor in a previous location of a resected small bowel GIST after 3 years.
But a ruptured small bowel GIST is certainly not the prime suspect under usual circumstances.