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After two successive injections, given 3-4 h apart based on the half-life of FSH (Laster, 1972), tissue samples of pituitary gland, uterus, ovary, oviduct, pancreas, glandular stomach and kidney were collected from the sacrificed hens.
The organs affected in the lower-dose groups included liver, glandular stomach, and nose (NTP 2000).
There was an increase in glandular stomach damage in four out of 20 female rats but none in the controls or male rats.