Regression analysis was done as the appropriate statistical technique for observing the dependence of number of granule cell
This exposure also leads to atrophy that is characterized by specific targeting of glutaminergic and GABAergic precursor cells of the cerebellum (especially granule cells
) resulting in misalignment of Purkinje cells and ectopic and multinucleated granule cells
This type of radial migration is mostly performed by neurons that have executed tangential migration underneath the pial surface and includes granule cells
of the cerebellum (6) and neurons of the pontine nuclei (PN) in the hindbrain.
Unlike the cerebellar granule cells
, purkinje cells are all generated before birth on E13 to E16, (13) and Purkinje cell dendritic outgrowth and synaptogenesis occur during postnatal three weeks.
Effects of cerebellar granule cell
depletion on spatial learning and memory in an avoidance conditioning task: Studies in postnatally X-irradiated rats.
Some FGF2-treated cells also expressed markers for the rhombic lip--the structure from which granule cells
develop and migrate, and a marker specific to migrating granule precursors by week seven.
LTD is accompanied by the reduced quantal size of excitatory synaptic currents at synapses between a granule cell
and a Purkinje cell, (45) and by the reduced ionotropic glutamate receptor responsiveness of a Purkinje cell.
Productive infection of cerebellar granule cell
neurons by JC virus in an HIV+ individual.
Dentate granule cell
neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus.
Incoming signals are transmitted by granule cells
in the dentate gyrus to pyramid cells in the CA3 region and from these to pyramid cells in the CA1 region.
Radiation-induced apoptotic and necrotic cell death of granule cells
and Purkinje cells were inhibited significantly by alpha-lipoic acid pretreatment.
As reported in this month's issue, a research group exposed cultures of immature neurons known as granule cells
and the more developed and more abundant astrocytes to sublethal doses of two well-characterized alkylating genotoxicants: methylazoxymethanol (MAM), a highly toxic compound synthesized from the poison found in plants called cycads, and nitrogen mustard (HN2), a chemotherapeutic agent.